The main research objectives of CAPSTONE is to deliver disruptive therapeutic innovation in two areas – autoimmune diseases and cancer – based on scientific excellence with high interdisciplinary and intersectoral permeability.

The research will be articulated into 3 workpackages:

  • WP3 Functions of ERAP
  • WP4 ERAP and diseases
  • WP5 Chemical probes and leads targeting ERAP
By targeting events upstream of immune response, CAPSTONE wishes to provide a way to to boost cancer immunotherapy and tame autoimmune conditions which there is a high therapeutic need.